INMD- Nematodes in the digestive system

INMD- Nematodes in the digestive system


Nematode infections are present on a world scale and cause major pathological problems in ruminants having an impact on health and well being in production animals and therefore effecting farm economics.

Synthetic anthelmintics have long since been the preferred method of control of nematodes. This has encouraged development of resistance to treatment options, which has lead to the need to find alternative solutions to chemical treatments in addition to demands from society to decrease chemical use in food production. This requires a better understanding of the host pathogen interactions. The latest concept is to explore the use of foods having positive health benefits. To explore this concept, the group studying dairy producing goats and sheep, fed with foraged vegetables that are high in tannins and polyphenols, which are believed to have an effect in nematodal infections.


JACKSON F., HOSTE H. 2010. In vitro methods for the primary screening of plant products for direct activity against ruminant gastrointestinal nematodes. In “In vitro screening of plant resources for extra nutritional attributes in ruminants: nuclear and related methodologies”  P.E.Vercoe, HPS Makkar and AC Schlink (Editors). FAO/IAEA Springer Edition, pp 24-45

HOSTE H., et al. 2012. Direct and indirect effects of bioactive legume forages against parasitic infections: experiences with tropical and temperate forages. Vet. Parasitol. 186, 18-27.

HOSTE H., et al 2015. Tannin containing legumes as a model for nutraceuticals against digestive parasites in livestock. Vet. Parasitol. 212, 5-17.

HOSTE H., et al 2016. Interactions between nutrition and infections with Haemonchus contortus (and related gastrointestinal nematodes) in small ruminants. Gasser R. and von Samson-Himmelstjersterna G. Eds  Adv. Parasitol. VOL 93 pp. 239–351.

QUIJADA J., FRYGANAS C., ROPIAK H. M., RAMSAY A, MUELLER-HARVEY I, HOSTE H. 2015 Anthelmintic activities against Haemonchus contortus or Trichostrongylus colubriformis are influenced by different structural features of condensed tannins J. Agr. Food. Chem. 63, 6346-6354.


Scientifique: H. Hoste (DR2 INRA)  ITA : S. Ketavong (TR, INRA), E.Pardo  (AJT, ENVT)…


Contact : Hervé HOSTE, animateur de l’équipe INMD, h.hoste@envt.fr

Liens UMT SPR : http://idele.fr/reseaux-et-partenariats/unites-mixtes-technologiques/umt-sante-des-petits-ruminants.html